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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2088
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh3a1
Name: aldehyde dehydrogenase 3 family, member A1
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh3a1increases metabolic processingISOAldh3a1 (Mus musculus)6480464CTDALDH3A1 protein results in increased metabolism of AcetaldehydePMID:21256123
Aldh3a1increases oxidationISOALDH3A1 (Homo sapiens)6480464CTDALDH3A1 protein results in increased oxidation of AcetaldehydePMID:18940187
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