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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2037
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adcyap1
Name: adenylate cyclase activating polypeptide 1
Acc ID: CHEBI:64629
Term: 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine
Definition: An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
Chemical ID: MESH:C015952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adcyap1increases response to substanceISOAdcyap1 (Mus musculus)6480464CTDADCYAP1 gene mutant form results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylaminePMID:24586556
Adcyap1multiple interactionsISOAdcyap1 (Mus musculus)6480464CTDADCYAP1 gene mutant form promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of FOS protein]PMID:24586556
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