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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2023
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acp3
Name: acid phosphatase 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acp3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ACP3 mRNA; bisphenol A results in decreased expression of ACP3 proteinPMID:12810577 PMID:25181051 PMID:32145629
Acp3increases activityEXP 6480464CTDbisphenol A results in increased activity of ACP3 proteinPMID:30526071
Acp3increases expressionISOAcp3 (Mus musculus)6480464CTDbisphenol A results in increased expression of ACP3 mRNAPMID:32156529
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