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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2018
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acly
Name: ATP citrate lyase
Acc ID: CHEBI:16196
Term: oleic acid
Definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
Chemical ID: MESH:D019301
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aclydecreases expressionISOACLY (Homo sapiens)6480464CTDOleic Acid results in decreased expression of ACLY mRNAPMID:31340670
Aclymultiple interactionsISOACLY (Homo sapiens)6480464CTD[[Vehicle Emissions results in increased abundance of Particulate Matter] which co-treated with Oleic Acid] results in decreased expression of ACLY mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNAPMID:30611723 PMID:31340670
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