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GENE - TERM ANNOTATION REPORT

RGD ID: 18901035
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: GO:0004222
Term: metalloendopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp13 ISOMmp13 (Rattus norvegicus)9068941RGD PMID:17941091 PMID:8910479 REF_RGD_ID:2296055 REF_RGD_ID:2298541
Mmp13enablesIEAUniProtKB:P33435 or UniProtKB:P45452 or ensembl:ENSMUSP00000015394 or ensembl:ENSP00000260302150520179Ensembl GO_REF:0000107
Mmp13enablesIEAInterPro:IPR001818 or InterPro:IPR021158 or InterPro:IPR021190150520179InterPro GO_REF:0000002
Mmp13enablesIEAPANTHER:PTHR10201:SF165150520179TreeGrafter GO_REF:0000118
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