GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Wnt1 | multiple interactions | EXP | | 6480464 | CTD | [Paraquat co-treated with Maneb] results in decreased expression of WNT1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of WNT1 protein | PMID:29152652 | Wnt1 | increases expression | ISO | Wnt1 (Mus musculus) | 6480464 | CTD | Paraquat results in increased expression of WNT1 mRNA; Paraquat results in increased expression of WNT1 protein | PMID:32462952 | Wnt1 | multiple interactions | ISO | Wnt1 (Mus musculus) | 6480464 | CTD | MIR140 mRNA inhibits the reaction [Paraquat results in increased expression of WNT1 protein]; Xuebijing inhibits the reaction [Paraquat results in increased expression of WNT1 mRNA]; Xuebijing inhibits the reaction [Paraquat results in increased expression of WNT1 protein] | PMID:32462952 | Wnt1 | multiple interactions | ISO | WNT1 (Homo sapiens) | 6480464 | CTD | WNT1 protein inhibits the reaction [Paraquat results in decreased expression of AXIN1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CCND1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CRTC2 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD4 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of LEF1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of MTOR mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of MYC mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of TCF7L1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of ATG5 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BECN1 mRNA] | PMID:30171970 | | ||||||||||||||||||||||
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