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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1597195
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wnt1
Name: Wnt family member 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt1multiple interactionsISOWnt1 (Mus musculus)6480464CTD[Folic Acid co-treated with sodium arsenite] results in increased methylation of WNT1 mRNAPMID:22959928
Wnt1multiple interactionsISOWNT1 (Homo sapiens)6480464CTD[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of WNT1 mRNA; [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of WNT1 mRNAPMID:12634122 PMID:23192986
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