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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595126
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Uqcr10
Name: ubiquinol-cytochrome c reductase, complex III subunit X
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Uqcr10affects expressionISOUQCR10 (Homo sapiens)6480464CTDDoxorubicin affects the expression of UQCR10 proteinPMID:29385562
Uqcr10decreases expressionISOUqcr10 (Mus musculus)6480464CTDDoxorubicin results in decreased expression of UQCR10 mRNAPMID:26873546
Uqcr10increases expressionISOUQCR10 (Homo sapiens)6480464CTDDoxorubicin results in increased expression of UQCR10 mRNAPMID:29803840
Uqcr10multiple interactionsISOUqcr10 (Mus musculus)6480464CTD[Doxorubicin co-treated with Dexrazoxane] results in increased expression of UQCR10 mRNAPMID:26873546
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