GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Smurf1 | decreases activity | ISO | SMURF1 (Homo sapiens) | 6480464 | CTD | Enzyme Inhibitors results in decreased activity of SMURF1 protein | PMID:30587574 | Smurf1 | multiple interactions | ISO | SMURF1 (Homo sapiens) | 6480464 | CTD | Enzyme Inhibitors inhibits the reaction [SMURF1 protein results in increased degradation of RHOA protein]; Enzyme Inhibitors inhibits the reaction [SMURF1 protein results in increased degradation of SMAD1 protein]; Enzyme Inhibitors inhibits the reaction [SMURF1 protein results in increased ubiquitination of and results in increased degradation of RHOB protein] | PMID:30587574 | |
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