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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1594565
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trmt10a
Name: tRNA methyltransferase 10A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trmt10adecreases expressionISOTRMT10A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of TRMT10A mRNAPMID:32234424
Trmt10aincreases expressionISOTrmt10a (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of TRMT10A mRNAPMID:19770486
Trmt10aincreases methylationISOTRMT10A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of TRMT10A 3' UTRPMID:27901495
Trmt10aincreases methylationISOTrmt10a (Mus musculus)6480464CTDBenzo(a)pyrene results in increased methylation of TRMT10A 3' UTR; Benzo(a)pyrene results in increased methylation of TRMT10A exonPMID:27901495
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