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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587893
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H1f2
Name: H1.2 linker histone, cluster member
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H1f2increases expressionEXP 6480464CTDEstradiol results in increased expression of H1F2 proteinPMID:32145629
H1f2increases expressionISOH1-2 (Homo sapiens)6480464CTDEstradiol results in increased expression of H1-2 mRNAPMID:20106945 PMID:21632981
H1f2multiple interactionsISOH1-2 (Homo sapiens)6480464CTD[Estradiol co-treated with Norethindrone Acetate] results in increased expression of H1-2 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of H1-2 mRNAPMID:17404688 PMID:22217510
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