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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566295
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh16a1
Name: aldehyde dehydrogenase 16 family, member A1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh16a1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ALDH16A1 mRNA; bisphenol A results in decreased expression of ALDH16A1 proteinPMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
Aldh16a1increases expressionEXP 6480464CTDbisphenol A results in increased expression of ALDH16A1 mRNAPMID:25181051
Aldh16a1decreases expressionISOALDH16A1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of ALDH16A1 mRNA; bisphenol A results in decreased expression of ALDH16A1 proteinPMID:33670352 PMID:34186270
Aldh16a1increases expressionISOAldh16a1 (Mus musculus)6480464CTDbisphenol A results in increased expression of ALDH16A1 mRNAPMID:33221593
Aldh16a1multiple interactionsISOALDH16A1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of ALDH16A1 genePMID:31601247
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