Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

RGD ID: 1566025
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pinx1
Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Acc ID: GO:0005730
Term: nucleolus
Definition: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pinx1located_inISOPINX1 (Homo sapiens)1624291RGD PMID:11701125 PMID:19265708 PMID:19393617 PMID:21119197 PMID:24415760

PMID:11701125 PMID:19265708 PMID:19393617 PMID:21119197 PMID:24415760
Pinx1located_inISOPINX1 (Homo sapiens) or UniProtKB:Q96BK5-11624291RGD GO_REF:0000052
Pinx1located_inIEAUniProtKB:Q96BK5 or ensembl:ENSP000003189661600115EnsemblGO_REF:0000107

GO_REF:0000107
Pinx1is_active_inIBAPANTHER:PTN000567695 or TAIR:locus:2024608 or UniProtKB:Q5T3I0 or UniProtKB:Q96BK5 or ZFIN:ZDB-GENE-030515-21600115GO_CentralGO_REF:0000033

GO_REF:0000033
Go Back to source page   Continue to Ontology report