GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pinx1 | affects methylation | ISO | PINX1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of PINX1 intron | PMID:30157460 | Pinx1 | increases expression | ISO | Pinx1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of PINX1 mRNA | PMID:15034205 | Pinx1 | multiple interactions | ISO | Pinx1 (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PINX1 mRNA; AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of PINX1 mRNA] | PMID:15034205 PMID:27858113 | |
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