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GENE - TERM ANNOTATION REPORT

RGD ID: 1563968
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndp
Name: norrin cystine knot growth factor NDP
Acc ID: GO:0062023
Term: collagen-containing extracellular matrix
Definition: An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
Definition Source(s): GOC:BHF, GOC:rph, PMID:21123617
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndplocated_inISONDP (Homo sapiens)1624291RGD PMID:15035989

PMID:15035989
Ndplocated_inISONdp (Mus musculus)1624291RGD MGI:3621833 PMID:15035989

MGI:3621833 PMID:15035989
Ndpis_active_inIBAMGI:102570 or PANTHER:PTN008411210 or UniProtKB:Q006041600115GO_CentralGO_REF:0000033

GO_REF:0000033
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