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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562852
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stra8
Name: stimulated by retinoic acid 8
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stra8increases expressionEXP 6480464CTDTretinoin results in increased expression of STRA8 mRNAPMID:17303670
Stra8increases expressionISOSTRA8 (Homo sapiens)6480464CTDTretinoin results in increased expression of STRA8 mRNAPMID:21674038
Stra8increases expressionISOStra8 (Mus musculus)6480464CTDTretinoin results in increased expression of STRA8 mRNAPMID:16461896 PMID:16574651 PMID:16604517 PMID:18425777 PMID:22190708 PMID:34942354 PMID:36189433
Stra8multiple interactionsISOStra8 (Mus musculus)6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of STRA8 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of STRA8 mRNA; [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STRA8 mRNA; AGN 193109 inhibits the reaction [Tretinoin results in increased expression of STRA8 mRNA]PMID:16574651 PMID:30951980 PMID:36189433
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