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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561737
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rnf144a
Name: ring finger protein 144A
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rnf144aaffects methylationISORNF144A (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of RNF144A 5' UTR; Benzo(a)pyrene affects the methylation of RNF144A promoterPMID:27901495
Rnf144adecreases expressionISORNF144A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of RNF144A mRNAPMID:20106945 PMID:21632981
Rnf144adecreases expressionISORnf144a (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of RNF144A mRNAPMID:21569818
Rnf144adecreases methylationISORNF144A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of RNF144A 3' UTRPMID:27901495
Rnf144aincreases expressionISORNF144A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of RNF144A mRNAPMID:30453624
Rnf144amultiple interactionsISORnf144a (Mus musculus)6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of RNF144A mRNAPMID:27858113
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