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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561419
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arhgap30
Name: Rho GTPase activating protein 30
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arhgap30decreases expressionISOArhgap30 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ARHGAP30 mRNAPMID:21569818
Arhgap30increases expressionISOARHGAP30 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of ARHGAP30 mRNAPMID:32234424
Arhgap30increases expressionISOArhgap30 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of ARHGAP30 mRNAPMID:22228805
Arhgap30increases methylationISOARHGAP30 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of ARHGAP30 exonPMID:27901495
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