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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558619
Species: Mus musculus
RGD Object: Gene
Symbol: Ctsb
Name: cathepsin B
Acc ID: CHEBI:59219
Term: ceruletide
Definition: A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.
Chemical ID: MESH:D002108
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctsbaffects localizationISOCtsb (Rattus norvegicus)6480464CTDCeruletide affects the localization of CTSB proteinPMID:17941083
Ctsbmultiple interactionsISOCtsb (Rattus norvegicus)6480464CTDsodium arsenite inhibits the reaction [Ceruletide affects the localization of CTSB protein]PMID:17941083
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