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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550694
Species: Mus musculus
RGD Object: Gene
Symbol: F8
Name: coagulation factor VIII
Acc ID: CHEBI:33629
Term: aluminium(0)
Definition: An elemental aluminium that has formula Al.
Chemical ID: MESH:D000535
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F8affects foldingISOF8 (Homo sapiens)6480464CTDAluminum affects the folding of F8 proteinPMID:15349964
F8multiple interactionsISOF8 (Homo sapiens)6480464CTD[Aluminum promotes the reaction [F8 protein binds to F8 protein]] which results in decreased activity of F8 proteinPMID:15349964
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