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GENE - TERM ANNOTATION REPORT

RGD ID: 14162513
Species: Sus scrofa
RGD Object: Gene
Symbol: KDM3A
Name: lysine demethylase 3A
Acc ID: GO:0003712
Term: transcription coregulator activity
Definition: A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
Definition Source(s): GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KDM3AenablesIEAUniProtKB:Q6PCM1 or ensembl:ENSMUSP00000128789150520179Ensembl GO_REF:0000107
KDM3AenablesIBAMGI:96223 or MGI:98847 or PANTHER:PTN000284569 or Hr (Rattus norvegicus)150520179GO_Central GO_REF:0000033
KDM3AenablesIEAPANTHER:PTHR12549:SF7150520179TreeGrafter GO_REF:0000118
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