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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359697
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oas2
Name: 2'-5' oligoadenylate synthetase 2
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oas2increases expressionISOOAS2 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of OAS2 mRNAPMID:35811015
Oas2increases expressionISOOas2 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of OAS2 mRNAPMID:22687549 PMID:25890327 PMID:26582142
Oas2multiple interactionsISOOAS2 (Homo sapiens)6480464CTDS-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of OAS2 mRNA]PMID:35811015
Oas2multiple interactionsISOOas2 (Mus musculus)6480464CTDgenipin inhibits the reaction [Lipopolysaccharides results in increased expression of OAS2 mRNA]PMID:22687549
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