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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359613
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Creb3l1
Name: cAMP responsive element binding protein 3-like 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Creb3l1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CREB3L1 mRNAPMID:33387578
Creb3l1affects expressionISOCreb3l1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CREB3L1 mRNAPMID:21570461 PMID:24058054 PMID:26377647
Creb3l1increases expressionISOCreb3l1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CREB3L1 mRNAPMID:18691609 PMID:19933214 PMID:26290441
Creb3l1multiple interactionsISOCreb3l1 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of CREB3L1 mRNAPMID:25975270
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