GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atg5 | multiple interactions | EXP | | 6480464 | CTD | ATG5 protein affects the reaction [Cadmium results in decreased expression of SQSTM1 protein]; ATG5 protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]; ATG5 protein affects the reaction [Cadmium results in increased expression of DDIT3 protein] | PMID:27658547 | Atg5 | affects response to substance | ISO | Atg5 (Mus musculus) | 6480464 | CTD | ATG5 protein affects the susceptibility to Cadmium | PMID:37506864 | Atg5 | increases expression | ISO | Atg5 (Mus musculus) | 6480464 | CTD | Cadmium results in increased expression of ATG5 mRNA; Cadmium results in increased expression of ATG5 protein | PMID:27492225 PMID:37148155 | Atg5 | multiple interactions | ISO | ATG5 (Homo sapiens) | 6480464 | CTD | ATG5 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; ATG5 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MTOR protein] | PMID:36336208 | Atg5 | multiple interactions | ISO | Atg5 (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATG5 protein; ATG5 protein affects the reaction [Cadmium results in increased cleavage of CASP3 protein]; ATG5 protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]; Cadmium inhibits the reaction [ATG5 protein affects the expression of KIT protein]; Cadmium inhibits the reaction [ATG5 protein affects the expression of ZBTB16 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of ALDH1A1 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of ALDH1A2 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of DDX4 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of RARA protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of STRA8 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of SYCP3 protein]; Cadmium promotes the reaction [ATG5 protein affects the expression of WT1 protein] | PMID:29111403 PMID:31862506 PMID:37506864 | | ||||||||||||||||||||||
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