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GENE - TERM ANNOTATION REPORT

RGD ID: 1354267
Species: Homo sapiens
RGD Object: Gene
Symbol: PIGS
Name: phosphatidylinositol glycan anchor biosynthesis class S
Acc ID: GO:0042765
Term: GPI-anchor transamidase complex
Definition: An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.
Definition Source(s): GOC:jl, GOC:rb, PMID:12802054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PIGSlocated_inIPI 150520179ComplexPortal PMID:12802054

PMID:12802054
PIGSpart_ofIEAUniProtKB:Q6PD26 or ensembl:ENSMUSP00000044871150520179Ensembl GO_REF:0000107
PIGSpart_ofIBAFB:FBgn0265190 or MGI:2687325 or PANTHER:PTN000472159 or SGD:S000002842 or UniProtKB:Q96S52150520179GO_Central GO_REF:0000033
PIGSpart_ofIEAInterPro:IPR019540150520179InterPro GO_REF:0000002
PIGSpart_ofIEAPANTHER:PTHR21072:SF13150520179TreeGrafter GO_REF:0000118
PIGSpart_ofIDA 150520179UniProt PMID:11483512 PMID:12802054

PMID:11483512 PMID:12802054
PIGSpart_ofTAS 150520179UniProt PMID:15713669

PMID:15713669
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