GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL6 | increases expression | ISO | Il6 (Mus musculus) | 6480464 | CTD | Cholesterol results in increased expression of IL6 mRNA; Cholesterol results in increased expression of IL6 protein | PMID:19028402 | IL6 | multiple interactions | ISO | Il6 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with bisphenol A co-treated with Cholesterol] results in increased secretion of IL6 protein; Cholesterol inhibits the reaction [Irbesartan results in increased expression of IL6 mRNA]; Cholesterol inhibits the reaction [Irbesartan results in increased expression of IL6 protein] | PMID:19028402 PMID:33239236 | IL6 | multiple interactions | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | [Cholesterol co-treated with Particulate Matter] results in increased expression of IL6 mRNA; alpha-Linolenic Acid inhibits the reaction [Cholesterol promotes the reaction [Particulate Matter results in increased expression of IL6 protein]]; Cholesterol promotes the reaction [Particulate Matter results in increased expression of IL6 protein] | PMID:30672636 | | ||||||||||||||||||||||
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