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GENE - TERM ANNOTATION REPORT

RGD ID: 1352369
Species: Homo sapiens
RGD Object: Gene
Symbol: ORMDL3
Name: ORMDL sphingolipid biosynthesis regulator 3
Acc ID: GO:0035339
Term: SPOTS complex
Definition: A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.
Definition Source(s): PMID:20182505
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ORMDL3part_ofIBAPANTHER:PTN000292374 or SGD:S000003270 or SGD:S000004342 or UniProtKB:Q8N138150520179GO_Central GO_REF:0000033
ORMDL3part_ofIDA 150520179MGI PMID:20182505 PMID:25691431

PMID:20182505 PMID:25691431
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