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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352369
Species: Homo sapiens
RGD Object: Gene
Symbol: ORMDL3
Name: ORMDL sphingolipid biosynthesis regulator 3
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ORMDL3affects expressionISOOrmdl3 (Mus musculus)6480464CTDPhenobarbital affects the expression of ORMDL3 mRNAPMID:23091169
ORMDL3increases expressionISOOrmdl3 (Mus musculus)6480464CTDPhenobarbital results in increased expression of ORMDL3 mRNAPMID:19850644
ORMDL3multiple interactionsISOOrmdl3 (Mus musculus)6480464CTDNR1I3 protein promotes the reaction [Phenobarbital results in increased expression of ORMDL3 mRNA]PMID:19850644
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