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GENE - TERM ANNOTATION REPORT

RGD ID: 1351773
Species: Homo sapiens
RGD Object: Gene
Symbol: CDH11
Name: cadherin 11
Acc ID: GO:0005912
Term: adherens junction
Definition: A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
Definition Source(s): GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDH11is_active_inIBAMGI:105057 or MGI:88354 or MGI:88355 or MGI:88356 or PANTHER:PTN000616280 or Cdh2 (Rattus norvegicus) or UniProtKB:P10288 or UniProtKB:P12830 or UniProtKB:P19022 or UniProtKB:P33151 or ZFIN:ZDB-GENE-010606-1150520179GO_Central GO_REF:0000033
CDH11located_inIEAPANTHER:PTHR24027:SF85150520179TreeGrafter GO_REF:0000118
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