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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348437
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:76591
Term: (25R)-cholest-5-ene-3beta,26-diol
Definition: A 26-hydroxycholesterol in which the 25-position has R-configuration.
Chemical ID: MESH:C076996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9increases expressionEXP 6480464CTD27-hydroxycholesterol results in increased expression of MMP9 mRNAPMID:24802026
MMP9multiple interactionsEXP 6480464CTDQuercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of MMP9 mRNA]PMID:24802026
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