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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348437
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:34310
Term: (24S)-24-hydroxycholesterol
Definition: A 24-hydroxycholesterol that has S configuration at position 24. It is the major metabolic breakdown product of cholesterol in the brain.
Chemical ID: MESH:C044563
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9increases expressionEXP 6480464CTD24-hydroxycholesterol results in increased expression of MMP9 mRNAPMID:24802026
MMP9multiple interactionsEXP 6480464CTDQuercetin analog inhibits the reaction [24-hydroxycholesterol results in increased expression of MMP9 mRNA]PMID:24802026
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