GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP2B6 | increases activity | EXP | | 6480464 | CTD | Omeprazole results in increased activity of CYP2B6 protein | PMID:19118567 | CYP2B6 | increases expression | EXP | | 6480464 | CTD | Omeprazole results in increased expression of CYP2B6 mRNA | PMID:17954527 PMID:19118567 PMID:22524704 | CYP2B6 | affects expression | ISO | Cyp2b3 (Rattus norvegicus) | 6480464 | CTD | Omeprazole affects the expression of CYP2B3 mRNA | PMID:19483382 | CYP2B6 | decreases activity | ISO | Cyp2b10 (Mus musculus) | 6480464 | CTD | Omeprazole results in decreased activity of CYP2B10 protein | PMID:18420780 | |
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