GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpbar1 | increases response to substance | EXP | | 6480464 | CTD | GPBAR1 protein results in increased susceptibility to Lithocholic Acid | PMID:23041323 | Gpbar1 | multiple interactions | EXP | | 6480464 | CTD | Lithocholic Acid binds to and results in increased activity of GPBAR1 protein | PMID:21454404 PMID:23041323 | Gpbar1 | affects binding | ISO | GPBAR1 (Homo sapiens) | 6480464 | CTD | Lithocholic Acid binds to GPBAR1 protein | PMID:23566200 | Gpbar1 | increases expression | ISO | GPBAR1 (Homo sapiens) | 6480464 | CTD | Lithocholic Acid results in increased expression of GPBAR1 mRNA | PMID:25055961 | Gpbar1 | multiple interactions | ISO | GPBAR1 (Homo sapiens) | 6480464 | CTD | [Lithocholic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; Lithocholic Acid analog binds to and results in increased activity of GPBAR1 protein; Lithocholic Acid binds to and results in increased activity of GPBAR1 protein | PMID:17963371 PMID:18180267 PMID:20023205 | |
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