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GENE - TERM ANNOTATION REPORT

RGD ID: 1322810
Species: Homo sapiens
RGD Object: Gene
Symbol: FANCA
Name: FA complementation group A
Acc ID: GO:0043240
Term: Fanconi anaemia nuclear complex
Definition: A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Definition Source(s): GOC:jl, PMID:12093742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FANCAlocated_inNAS 150520179ComplexPortal PMID:22343915

PMID:22343915
FANCApart_ofIBAPANTHER:PTN001382355 or UniProtKB:O15360150520179GO_Central GO_REF:0000033
FANCApart_ofIEAInterPro:IPR003516150520179InterPro GO_REF:0000002
FANCApart_ofIEAPANTHER:PTHR12047:SF2150520179TreeGrafter GO_REF:0000118
FANCApart_ofIDA 150520179UniProt PMID:20347428 PMID:22266823 PMID:22343915 PMID:22705371

PMID:20347428 PMID:22266823 PMID:22343915 PMID:22705371
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