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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320708
Species: Mus musculus
RGD Object: Gene
Symbol: Sox7
Name: SRY (sex determining region Y)-box 7
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox7decreases expressionEXP 6480464CTDProgesterone results in decreased expression of SOX7 mRNAPMID:17556502
Sox7multiple interactionsEXP 6480464CTDNCOA2 protein affects the reaction [Progesterone results in decreased expression of SOX7 mRNA]PMID:17556502
Sox7multiple interactionsISOSOX7 (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in increased expression of SOX7 mRNAPMID:20660070
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