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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319195
Species: Mus musculus
RGD Object: Gene
Symbol: Stat6
Name: signal transducer and activator of transcription 6
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat6multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of STAT6 mRNAPMID:37325564
Stat6multiple interactionsISOSTAT6 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of STAT6 protein; MitoTEMPO inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of STAT6 protein]; PPARG protein inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of STAT6 protein]PMID:32917723
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