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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317427
Species: Homo sapiens
RGD Object: Gene
Symbol: CEMIP2
Name: cell migration inducing hyaluronidase 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEMIP2decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of CEMIP2 3' UTRPMID:27901495
CEMIP2increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CEMIP2 mRNA; Benzo(a)pyrene results in increased expression of CEMIP2 proteinPMID:21632981 PMID:21871943 PMID:22316170 PMID:26238291 PMID:30453624 PMID:33278487
CEMIP2decreases expressionISOCemip2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CEMIP2 mRNAPMID:19770486 PMID:21569818
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