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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315773
Species: Mus musculus
RGD Object: Gene
Symbol: Igtp
Name: interferon gamma induced GTPase
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igtpaffects expressionEXP 6480464CTDLipopolysaccharides affects the expression of IGTP mRNAPMID:24056979
Igtpincreases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of IGTP mRNAPMID:17321000 PMID:25890327 PMID:27339419
Igtpmultiple interactionsEXP 6480464CTD(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IGTP mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IGTP mRNA]PMID:24056979 PMID:25890327
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