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GENE - TERM ANNOTATION REPORT

RGD ID: 1312517
Species: Homo sapiens
RGD Object: Gene
Symbol: ERCC4
Name: ERCC excision repair 4, endonuclease catalytic subunit
Acc ID: GO:0000724
Term: double-strand break repair via homologous recombination
Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Definition Source(s): GOC:elh, PMID:10357855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ERCC4involved_inIBAPANTHER:PTN000015911 or PomBase:SPCC970.01 or TAIR:locus:2163011 or UniProtKB:Q92889 or dictyBase:DDB_G0284419150520179GO_Central GO_REF:0000033
ERCC4involved_inIEAPANTHER:PTHR10150:SF0150520179TreeGrafter GO_REF:0000118
ERCC4involved_inIMP 150520179UniProt PMID:14728600

PMID:14728600
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