GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rgma | affects methylation | ISO | RGMA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of RGMA intron; Benzo(a)pyrene affects the methylation of RGMA promoter | PMID:27901495 PMID:30157460 | Rgma | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RGMA mRNA | PMID:32234424 | Rgma | increases expression | ISO | Rgma (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of RGMA mRNA | PMID:22228805 | Rgma | increases methylation | ISO | RGMA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of RGMA 3' UTR; Benzo(a)pyrene results in increased methylation of RGMA exon | PMID:27901495 | Rgma | multiple interactions | ISO | Rgma (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RGMA mRNA] | PMID:22228805 | |
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