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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c2increases expressionISOAKR1C2 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of AKR1C2 mRNA; sodium arsenite results in increased expression of AKR1C2 proteinPMID:19696165 PMID:20886546 PMID:25493608 PMID:28595984 PMID:34032870
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