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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Acc ID: CHEBI:28952
Term: 5alpha-pregnane-3,20-dione
Definition: A C21-steroid hormone that is 5alpha-pregnane substituted by oxo groups at positions 3 and 20. It is a metabolite of progestrone.
Chemical ID: MESH:D043582
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c2affects reductionISOAKR1C2 (Homo sapiens)6480464CTDAKR1C2 protein affects the reduction of 5-alpha-DihydroprogesteronePMID:12604236
Akr1c2increases reductionISOAKR1C2 (Homo sapiens)6480464CTDAKR1C2 protein results in increased reduction of 5-alpha-DihydroprogesteronePMID:11995921
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