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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Acc ID: CHEBI:1712
Term: 3alpha-hydroxy-5beta-pregnan-20-one
Definition: The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.
Chemical ID: MESH:D011280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c2affects metabolic processingISOAKR1C2 (Homo sapiens)6480464CTDAKR1C2 protein affects the metabolism of PregnanolonePMID:12604236
Akr1c2increases reductionISOAKR1C2 (Homo sapiens)6480464CTDAKR1C2 protein results in increased reduction of PregnanolonePMID:11995921
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