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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c2affects expressionISOAKR1C2 (Homo sapiens)6480464CTDHydrogen Peroxide affects the expression of AKR1C2 mRNAPMID:23410634
Akr1c2increases expressionISOAKR1C2 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of AKR1C2 mRNAPMID:12414654
Akr1c2multiple interactionsISOAKR1C2 (Homo sapiens)6480464CTD[Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 mRNA; [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 proteinPMID:19320734
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