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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311666
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlnrd1
Name: talin rod domain containing 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlnrd1decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of TLNRD1 mRNAPMID:21839799
Tlnrd1decreases expressionISOTlnrd1 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TLNRD1 mRNAPMID:27195522
Tlnrd1decreases methylationISOTLNRD1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of MESDC1 promoterPMID:27901495
Tlnrd1increases expressionISOTLNRD1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of TLNRD1 mRNAPMID:22316170 PMID:26238291
Tlnrd1increases expressionISOTlnrd1 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of TLNRD1 mRNAPMID:22228805
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