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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311541
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp17
Name: matrix metallopeptidase 17
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp17affects expressionISOMmp17 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of MMP17 mRNAPMID:21570461 PMID:24680724
Mmp17decreases expressionISOMmp17 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of MMP17 mRNAPMID:19933214
Mmp17multiple interactionsISOMmp17 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to MMP17 promoter]PMID:19654925
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