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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310749
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfatc4
Name: nuclear factor of activated T-cells 4
Acc ID: CHEBI:34306
Term: 20-HETE
Definition: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20.
Chemical ID: MESH:C055987
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfatc4increases localizationEXP 6480464CTD20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 proteinPMID:16055480
Nfatc4multiple interactionsEXP 6480464CTDCyclosporine inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]PMID:16055480
Nfatc4increases localizationISONFATC4 (Homo sapiens)6480464CTD20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 proteinPMID:16055480
Nfatc4multiple interactionsISONFATC4 (Homo sapiens)6480464CTDCyclosporine inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]PMID:16055480
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