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GENE - TERM ANNOTATION REPORT

RGD ID: 1310252
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ano4
Name: anoctamin 4
Acc ID: GO:0005229
Term: intracellularly calcium-gated chloride channel activity
Definition: Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
Definition Source(s): GOC:mtg_transport, PMID:29236691
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ano4NOT|enablesISOAno4 (Mus musculus)1624291RGD MGI:5448512 PMID:22075693 PMID:23532839

MGI:5448512 PMID:22075693 PMID:23532839
Ano4enablesISOANO4 (Homo sapiens)1624291RGD PMID:22946059

PMID:22946059
Ano4enablesIBAPANTHER:PTN002642691 or UniProtKB:Q32M451600115GO_CentralGO_REF:0000033

GO_REF:0000033
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