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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309155
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fkbp5
Name: FKBP prolyl isomerase 5
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fkbp5increases expressionEXP 6480464CTDOzone results in increased expression of FKBP5 mRNAPMID:28623178 PMID:31397875 PMID:33662111 PMID:34051339 PMID:35737395
Fkbp5multiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of Ozone] which results in increased expression of FKBP5 mRNAPMID:37047376
Fkbp5increases expressionISOFkbp5 (Mus musculus)6480464CTDOzone results in increased expression of FKBP5 mRNAPMID:17460151 PMID:19555225
Fkbp5multiple interactionsISOFkbp5 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of FKBP5 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of FKBP5 mRNAPMID:34911549
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