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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3increases expressionISONlrp3 (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of NLRP3 mRNAPMID:17942915
Nlrp3multiple interactionsISONlrp3 (Mus musculus)6480464CTDMET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NLRP3 mRNA]PMID:17942915
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